High-strength,in situ-setting calcium phosphate composite with protein release
نویسندگان
چکیده
منابع مشابه
Preparation of in situ hardening composite microcarriers: Calcium phosphate cement combined with alginate for bone regeneration
Novel microcarriers consisting of calcium phosphate cement and alginate were prepared for use as three-dimensional scaffolds for the culture and expansion of cells that are effective for bone tissue engineering. The calcium phosphate cement-alginate composite microcarriers were produced by an emulsification of the composite aqueous solutions mixed at varying ratios (calcium phosphate cement pow...
متن کاملCell-mediated protein release from calcium-phosphate-coated titanium implants.
Implants used in dental and orthopaedic surgery should become osseointegrated into native bone. In an endeavour to potentiate bone formation, prostheses, coated with a coprecipitated layer of calcium phosphate and the osteogenic agent BMP-2, were implanted at an ectopic site in rats. Five weeks later, the implants were surrounded by a substantial mass of bone. Our findings indicate that the dru...
متن کاملLong-term cell-mediated protein release from calcium phosphate ceramics.
Efficient delivery of growth factors from carrier biomaterials depends critically on the release kinetics of the proteins that constitute the carrier. Immobilizing growth factors to calcium phosphate ceramics has been attempted by direct adsorption and usually resulted in a rapid and passive release of the superficially adherent proteins. The insufficient retention of growth factors limited the...
متن کاملDual-setting calcium phosphate cement modified with ammonium polyacrylate.
alpha-Tricalcium phosphate bone cement, as formerly designed and developed by Driessens et al., consists of a powder composed by alpha-tricalcium phosphate (alpha-TCP) and hydroxyapatite (HA) seeds, and an aqueous solution of Na2HPO4 as mixing liquid. After mixing powder and liquid, alpha-TCP dissolves into the liquid and calcium deficient hydroxyapatite (CDHA), more insoluble than the former, ...
متن کاملCALCIUM PHOSPHATE CEMENT: STUDY OF (BETA-TRICALCIUM PHOSPHATE, DICALCIUM PHOSPHATE AND CALCIUM CARBONATE SYSTEM
Calcium phosphate cements (CPCs), using B-tricalcium phosphate (ß-TCP, Ca3 (P04)2), dicalcium phosphate (DCP, CaHP04), calcium carbonate (Ca CO3), and hydroxylapatite (HAp, Ca10(P04)6(OH)2) as powder cement and disodium hydrogen phosphate (Na2HP04) solution as liquid component were prepared. After mixing the powder and liquid constituents, injectable and self-setting calcium phosphate cements (...
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ژورنال
عنوان ژورنال: Journal of Biomedical Materials Research Part A
سال: 2008
ISSN: 1549-3296,1552-4965
DOI: 10.1002/jbm.a.31347